Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli | Plasmodium falciparum |
Crystallization (Comment) | Organism |
---|---|
- |
Plasmodium falciparum |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
bestatin | - |
Plasmodium falciparum | |
N-[(2S,3R)-3-amino-2-hydroxy-4-(4-methoxyphenyl)butanoyl]-L-leucine | - |
Plasmodium falciparum | |
N-[(2S,3R)-3-amino-2-hydroxy-4-(naphthalen-2-yl)butanoyl]-L-leucine | - |
Plasmodium falciparum | |
N-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl]-L-norleucine | - |
Plasmodium falciparum | |
N-[(2S,3R)-3-amino-2-hydroxyheptanoyl]-L-leucine | - |
Plasmodium falciparum | |
N-[(2S,3R)-3-amino-4-[4-(benzyloxy)phenyl]-2-hydroxybutanoyl]-L-leucine | - |
Plasmodium falciparum | |
N2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl]-N6-[(benzyloxy)carbonyl]-L-lysine | - |
Plasmodium falciparum |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Plasmodium falciparum | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Plasmodium falciparum |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-leucyl-7-amido-4-methylcoumarin + H2O | - |
Plasmodium falciparum | L-leucine + 7-amino-4-methylcoumarin | - |
? |
Synonyms | Comment | Organism |
---|---|---|
M1 metalloaminopeptidase | - |
Plasmodium falciparum |
malaria M1 metalloaminopeptidase | - |
Plasmodium falciparum |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.000043 | - |
N-[(2S,3R)-3-amino-2-hydroxy-4-(4-methoxyphenyl)butanoyl]-L-leucine | pH 7.5, temperature not specified in the publication | Plasmodium falciparum | |
0.00019 | - |
bestatin | pH 7.5, temperature not specified in the publication | Plasmodium falciparum | |
0.00049 | - |
N-[(2S,3R)-3-amino-4-[4-(benzyloxy)phenyl]-2-hydroxybutanoyl]-L-leucine | pH 7.5, temperature not specified in the publication | Plasmodium falciparum | |
0.0009 | - |
N-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl]-L-norleucine | pH 7.5, temperature not specified in the publication | Plasmodium falciparum | |
0.00145 | - |
N2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl]-N6-[(benzyloxy)carbonyl]-L-lysine | pH 7.5, temperature not specified in the publication | Plasmodium falciparum | |
0.003 | - |
N-[(2S,3R)-3-amino-2-hydroxy-4-(naphthalen-2-yl)butanoyl]-L-leucine | pH 7.5, temperature not specified in the publication | Plasmodium falciparum | |
0.0053 | - |
N-[(2S,3R)-3-amino-2-hydroxyheptanoyl]-L-leucine | pH 7.5, temperature not specified in the publication | Plasmodium falciparum |